MP-SPR Navi™ 400 KONTIO
Semi-automated and modular
MP-SPR NaviTM 400 KONTIO is specially designed to measure cell adhesion and cell-based interactions in physiologically relevant conditions. The instrument is compatible with complex cell culture media and other crude samples.Product Category: SPR
Industry: Life Sciences, Particle and surface science
Supplier: Bionavis
Description
Features and benefits
- 4 fluidic channels for simultaneous measurements
- Two independent wavelength measurements from each fluidic channel, enabling detection of thickness and refractive index, conformational changes and cellular interactions
- Exceptionally wide angular range 40˚ – 78˚C enables measurements with complex cell culture media and other crude samples like serum and saliva. Cells can be directly cultured on the sensor slide surface or the sensor surface is modified and cells are introduced as a sample
- Controlled liquid flow conditions with peristaltic pump
- Manual filling of injection loops required
- Parallel or serial injections into fluidic channels
- 400 KONTIO is provided with a basic software package of MP-SPR Navi™ Control and DataViewer for convenient control of the instrument and basic analysis of the results. Advanced analysis modules are optional: MP-SPR Navi™ LayerSolver™ to determine thickness and refractive index from multiple wavelength measurements and TraceDrawer™ for MP-SPR Navi™ a powerful software for determination of affinity and kinetic constants and more
- MP-SPR Navi™ instruments utilize optical RI matching elastomer and therefore sensors are very easy to exchange. They can also be further analyzed with other methods, such as AFM or microscopy
- Open design enables convenient access to the easily removable flow-cell, as well as to tubing, pump and injection valves
- The instrument enables attachment of a separate autosampler, pump, degasser or even own microfluidic sample pre-processing cartridge
Whitepapers
Please see the Bionavis website for a series of application notes
https://www.bionavis.com/en/publication_type/application-notes/
Accessories
Flow-cells
We offer a wide variety of flow-cells suitable for specific applications. All flow-cells can be easily exchanged by the user.
Our standard flow-cells are available in a variety of materials (PDMS, PEEK, Kalrez) depending on application such as kinetic studies or material characterization. Inlet diameter of the tubings and fluidic channel volume is optimized for each purpose.
Our special flow-cells enable the combination of MP-SPR measurements with electrochemistry or fluorescence and the measurement of live cells. All our flow-cells enable measurements in air and liquid and our special gas flow-cell enables even measurements with pressurized gas.
Contact us for more information and to find the most suitable flow-cell for your measurements!
MP-SPR Navi™ Immobilizer
Our MP-SPR Navi™ Immobilizer is an especially designed stand-alone holder for chemical modifications and functionalization of MP-SPR Navi™ sensor surfaces. MP-SPR Navi™ Immobilizer is compatible with the MP-SPR Navi™ sensor slides and MP-SPR Navi™ sensor slide holder.
Read more about immobilizer in AN#130.
Contact us for more information on our MP-SPR Navi™ immobilizer.
We provide the only MP-SPR instruments on the market that can be equipped with multiple wavelengths!
MP-SPR measures uniquely same surface spot at two different wavelengths which enables thickness and refractive index measurements. This feature is useful in all MP-SPR applications but especially with material characterization, biophysics, and live cell studies.
All MP-SPR Navi™ instruments can be equipped with up to 2 different wavelengths in each channel. MP-SPR Navi™ 200 OTSO, 210A VASA and 220A NAALI instruments can be equipped with up to 4 different wavelengths in each channel.
Additional wavelength option should be selected together with the instrument.
Get most out of the feature and combine it with LayerSolver software.
If you already have MP-SPR Navi™ system, contact us to learn how to upgrade it with additional lasers!
We offer a wide range of sensor slides manufactured according to high quality standards
All BioNavis sensors are cut to 12х20 mm size to fit into the BioNavis sensor slide holder and thus sensors are compatible with all the SPR Navi™ and MP-SPR Navi™ instruments.
Please see the Bionavis website for the range and choose the best sensor surface for your measurements. https://www.bionavis.com/en/products/additional-options-and-consumables/sensor-slides/
BioNavis offers a variety of software for data collection with our MP-SPR Navi™ instruments and analysis of MP-SPR data
https://www.bionavis.com/en/products/additional-options-and-consumables/software/